Adherence to Buprenorphine Maintenance Treatment Program in Western Nepal

Cessation of methadone maintenance treatment using buprenorphine: transfer from methadone to buprenorphine and subsequent buprenorphine reductions.

BACKGROUND Buprenorphine is used in the treatment of opioid dependence. Due to its pharmacology, the transfer from methadone to buprenorphine may precipitate withdrawal symptoms. METHODS Methadone maintained patients with clinical indicators of stability who were seeking withdrawal from methadone were recruited from three Australian states. Patients on methadone doses between 30 and 40 mg wer...

Qualitative Study of Factors Affecting Adherence to Treatment in Substance-Dependent Individuals with Maintenance Treatment in Isfahan

Objective: The aim of this study was to qualitatively study the factors affecting adherence to treatment in substance-dependent individuals with methadone maintenance treatment in Isfahan. Method: This research was of qualitative type and thematic analysis. The statistical population included all substance-dependent individuals in addiction treatment centers with methadone in Isfahan in 2018. F...

A new delivery model to increase adherence to methadone maintenance treatment

Erectile dysfunction in men receiving methadone and buprenorphine maintenance treatment.

INTRODUCTION Use of opiates/opioids is associated with hypoactive sexual desire, erectile and orgasmic dysfunction. AIM To determine prevalence and investigate etiology of sexual dysfunction in men on methadone or buprenorphine maintenance treatment (MMT, BMT). MAIN OUTCOME MEASURES International Index of Erectile Function (IIEF), hormone assays, Beck Depression Inventory. METHODS A total...

Urinary excretion of buprenorphine, norbuprenorphine, buprenorphine-glucuronide, and norbuprenorphine-glucuronide in pregnant women receiving buprenorphine maintenance treatment.

BACKGROUND Buprenorphine (BUP) is under investigation as a medication therapy for opioid-dependent pregnant women. We investigated BUP and metabolite disposition in urine from women maintained on BUP during the second and third trimesters of pregnancy and postpartum. METHODS We measured BUP, norbuprenorphine (NBUP), buprenorphine glucuronide (BUP-Gluc), and NBUP-Gluc concentrations in 515 uri...